Vimovo

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

• Take one tablet twice a day, 30 minutes before meals

• Swallow tablets whole; do not crush or chew

• Do not exceed recommended dose

• Store below 25°C

• Keep in original packaging

• Keep out of reach of children

Ingredients

Active Ingredients:

• Naproxen 500mg

• Esomeprazole magnesium 20mg

Other Ingredients:

• Hypromellose

• Magnesium stearate

• Titanium dioxide

• Talc

• Polysorbate 80

• Iron oxide (colourant)

Side Effects

Common side effects may include:

• Indigestion

• Constipation or diarrhoea

• Headache

• Nausea

Serious (rare) side effects:

• Gastrointestinal bleeding

• Heart attack or stroke (rare but serious NSAID risks)

• Allergic reactions

• Liver or kidney problems

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not take Vimovo if you are allergic to naproxen, esomeprazole, or other NSAIDs. Not suitable for individuals with active ulcers, severe kidney impairment, or cardiovascular risks. Avoid during the third trimester of pregnancy. Use only under medical supervision with regular monitoring.

Vimovo modified-release tablets are a dual-action prescription medicine specifically designed to treat symptoms of chronic inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. These tablets are intended for patients who require long-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) but who also have a risk of developing gastrointestinal complications. Vimovo provides effective relief from pain and inflammation while reducing the potential for stomach ulcers and irritation.

How It Works
Each Vimovo tablet combines two active substances: naproxen, a potent NSAID, and esomeprazole magnesium, a proton pump inhibitor (PPI). Naproxen works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the production of prostaglandins that cause inflammation and pain. While NSAIDs are effective, they often increase the risk of gastric side effects. Esomeprazole addresses this concern by reducing the amount of acid produced in the stomach lining. This protective action significantly lowers the risk of gastrointestinal ulcers or bleeding, particularly in patients with a history of NSAID-related digestive issues.

Why Choose Vimovo
Vimovo simplifies treatment by combining two therapies into one convenient formulation. It offers both the anti-inflammatory and analgesic benefits of naproxen and the stomach-protective effects of esomeprazole, helping to avoid the need for multiple medications. This combination enhances adherence, improves symptom management, and offers reassurance for patients requiring extended NSAID use. The modified-release tablet ensures that the esomeprazole is absorbed before the naproxen is released, optimising gastrointestinal protection.

Important Note
Vimovo should only be taken under medical supervision and is not suitable for everyone. It must not be used by individuals with active or recent gastrointestinal bleeding, severe hepatic or renal impairment, or known allergies to NSAIDs or proton pump inhibitors. Patients with cardiovascular risk factors should discuss potential risks with their doctor. It is also not recommended during pregnancy, especially in the third trimester. Regular medical reviews are essential to ensure safe and effective treatment over time.