Indivina

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

• Take one tablet daily at the same time

• Do not skip or stop treatment without medical advice

• Swallow whole with water

• Take continuously without breaks

• Store below 25°C

• Keep in original packaging

• Keep out of reach of children

Ingredients

Active Ingredients (per tablet):

• Oestradiol (0.5mg / 1mg)

• Medroxyprogesterone acetate (2.5mg / 5mg depending on variant)

Other Ingredients:

• Lactose monohydrate

• Maize starch

• Magnesium stearate

• Hypromellose

• Macrogol

• Titanium dioxide

Side Effects

Common side effects may include:

• Headache

• Breast tenderness

• Nausea

• Bloating

Serious (rare) side effects:

• Blood clots

• Stroke or heart attack

• Breast or endometrial cancer

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not take Indivina if you have a history of breast cancer, unexplained vaginal bleeding, blood clots, liver disease, or if you are pregnant. Regularly review the need for treatment with your doctor. Report any new symptoms such as unexpected bleeding or breast changes promptly.

Indivina is a continuous combined hormone replacement therapy (HRT) designed for postmenopausal women who still have their uterus. It is prescribed to relieve common symptoms of menopause such as hot flushes, night sweats, mood swings, and vaginal dryness. Indivina provides both oestrogen and progestogen in a convenient once-daily oral tablet.

How It Works
Each Indivina tablet contains a combination of oestradiol, a naturally occurring form of oestrogen, and medroxyprogesterone acetate, a synthetic progestogen. Oestradiol helps to replenish declining hormone levels during menopause and alleviate associated symptoms. Medroxyprogesterone acetate protects the endometrial lining from overgrowth, reducing the risk of endometrial cancer linked with oestrogen-only therapy in women who still have their womb.

Why Choose Indivina
Indivina offers a well-established and effective solution for managing menopausal symptoms. It is suitable for women seeking continuous combined HRT and provides the benefit of daily dosing without cycle-related bleeding. With multiple strengths available, it allows tailored treatment to match individual hormone requirements. The oral format is convenient and familiar for many patients, offering flexibility and ease of administration.

Important Note
Indivina should not be used in women with known or suspected hormone-sensitive cancers, unexplained vaginal bleeding, untreated endometrial hyperplasia, or a history of venous thromboembolism. Before starting therapy, a thorough medical assessment is required. Regular follow-ups are essential to ensure continued safety and efficacy of treatment.