Utrogestan Capsules

Directions

Note: Always follow your doctor’s instructions and leaflet guidance.

• Sequential HRT (with monthly bleed):

  • 2 capsules daily at bedtime for 12 days each 28-day cycle

• Continuous HRT (no bleeding):

  • 1 capsule daily at bedtime continuously

Administration:

• Take with water, preferably on an empty stomach or at least 2 hours after food

• Take at bedtime to reduce drowsiness during the day

Storage:

• Store below 25°C

• Protect from light and moisture

• Keep out of reach of children

Ingredients

• Active Ingredient:

  • Micronised progesterone 100mg per capsule

• Key Excipients:

  • Sunflower oil

  • Soy lecithin (potential allergen)

  • Gelatin capsule shell

Side Effects

Common side effects:

• Drowsiness

• Breast tenderness

• Headache

• Bloating

Serious but rare:

• Allergic reactions

• Irregular bleeding

• Depression (seek GP review)

Discontinue if you experience unusual vaginal bleeding, jaundice, or mood changes.

Warnings

• Contraindications:

  • Undiagnosed vaginal bleeding

  • Active liver disease

  • Peanut or soy allergy

• Pregnancy/Breastfeeding:

  • Not recommended during pregnancy or lactation

• Drug Interactions:

  • May interact with antiepileptics, St. John’s Wort, and some antifungals

• Monitoring:

  • Annual HRT review recommended

Utrogestan 100mg Capsules contain micronised progesterone, a natural hormone used to complement oestrogen in hormone replacement therapy (HRT). It is suitable for postmenopausal women who have not had a hysterectomy. When oestrogen is used alone in HRT, it can increase the risk of endometrial hyperplasia and cancer. Progesterone like Utrogestan helps protect the lining of the uterus.

Utrogestan is taken orally and is commonly prescribed alongside transdermal oestrogen products such as Oestrogel or Estradot.

How It Works

Progesterone plays a crucial role in the menstrual cycle and maintaining uterine health. Utrogestan mimics the body’s own progesterone. When taken cyclically or continuously, it ensures that oestrogen-induced endometrial growth is counteracted, lowering the risk of abnormal bleeding or hyperplasia.

Because the progesterone is micronised, it is more efficiently absorbed by the body when taken orally.

Why Choose Utrogestan

Utrogestan is the only body-identical oral progesterone licensed for use in HRT in the UK. Unlike synthetic alternatives (like medroxyprogesterone), it is well-tolerated by most women and has a lower side effect profile.

Key benefits include:

Natural, body-identical hormone

Reduced risk of breast tenderness and mood changes

No synthetic additives or preservatives

Effective protection of the endometrium during HRT

Used in both sequential and continuous HRT regimens

Many women prefer Utrogestan for its natural profile and suitability for a personalised HRT plan.

Important Note

This medication is taken orally, typically at bedtime. Do not crush or chew the capsules. You may experience temporary drowsiness, so avoid driving if affected. Regular HRT reviews and monitoring are recommended. Always take it as prescribed in conjunction with an oestrogen treatment.